Guido delle Colonne (in Latin Guido de Columnis or de Columna) was an early 13th century Sicilian writer, living at Messina, who wrote in Latin. He is the author of a prose narrative of the Trojan War entitled Historia destructionis Troiae ("History of the destruction of Troy") that was based on De excidio Trojae historia written by Dares Phrygius and Ephemeridos belli Trojani written by Dictys Cretensis.
Dante (De vulgari eloquentia 2.5) named Guido as a poet in the vernacular, and in fact five poems by him in Italian survive.